Please browse i-mouse.org by using one of the sections below, which are split up into ontology resources, mouse databases and web services and mouse knockout resources.
Ontology resources for the Community
CASIMIR carried out a survey in summer 2007 to ascertain the sorts of database activities carried out by currently-active EC-funded mouse functional genomics projects and whether they are currently making use of community standards such a ontologies and minimum information standards for reporting experimental data. In a recent paper we report the results of the survey and discuss their consequences in the context of integration of these large projects into the wider data network. More...
One issue arising from this consultation was the perceived need for a resource listing relevant ontologies for mouse functional genomics and i-mouse.org was created as a resource to address this need. Link to Ontology Resources page
Mouse Resource Browser (MRB)
The MRB comprises a database of data and information resources of use to those interested in the biology and genetics of the laboratory mouse. Integration of data across many of these resources requires knowledge of the technical details of data structure and programmatic access, for example, and in addition to descriptions of the databases, URLs and links, we will bring together technical details to facilitate the construction of automatic work flows and data feeds. More...
Mouse knockout resources
The goal of EUCOMM is to generate collection of up to 20,000 mutated genes in mouse embryonic stem (ES) cells using conditional gene trapping and gene targeting approaches which will be made available to investigators world wide.
KOMP is a trans-NIH initiative to generate a public resource of mouse embryonic stem (ES) cells containing a null mutation in every gene in the mouse genome. Two groups have been funded by this program to generate knockout mouse lines: Regeneron Pharmaceuticals, Inc. and a collaborative team at the Children's Hospital Oakland Research Institute (CHORI), the University of California at Davis School of Veterinary Medicine, and the Wellcome Trust Sanger Institute.
NorCOMM (North American Conditional Mouse Mutagenesis project) is a large-scale research initiative focused on developing and distributing a library of mouse embryonic stem (ES) cell lines carrying single conditional knockout mutations across the mouse genome.